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Other Amino Acid Chemical Derivatives

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Amino acid side chains represent a broad range of functional groups and there are Other Amino Acid Chemical Derivatives which are sites of nonspecific reactivity during peptide synthesis. Because of this, many different protecting groups are required. Side chain protecting groups are known as permanent or semi-permanent protecting groups, because they can withstand the multiple cycles of chemical treatment during synthesis and are only removed during treatment with strong acids after peptide synthesis is completed.

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